Sue Marshall blogs about diabetes for Desang

Trail Begins for Drug Aiming to Regenerate Insulin Production | March 25, 2010

A human trial of a new drug aiming to regenerate insulin-producing cells in Type 1 diabetics is underway in America.

McGill University has begun its 24-patient Phase II human trial of a drug developed by Exsulin Corp that aims to regenerate insulin-producing cells in Type 1 diabetics, according to an article from Med City News.

Type 1 diabetes is an autoimmune disease in which the body’s immune system mistakenly identifies insulin-producing beta cells in the pancreas as foreign cells and destroys them. Without the cells, people with Type 1 diabetes cannot make insulin, the hormone responsible for regulating the amount of sugar in the blood. Therefore, they must inject themselves with insulin several times each day. Approximately 3 million people in the United States have Type 1 diabetes.

Exsulin’s drug aims to instruct certain cells in the pancreas to become insulin-producing cells. While this route wouldn’t provide a true cure for Type 1 diabetics because it can’t replace all of the lost insulin, but researchers hope it can help stabilize dramatic blood sugar fluctuations, which can lead to some of the disease’s worst complications.

via: Diabeties News Hound

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